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Biochem. Question

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1Biochem. Question Empty Biochem. Question Sat Oct 24, 2009 2:12 pm

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What is AGE? (Covered in diabetes lecture)

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2Biochem. Question Empty Re: Biochem. Question Sat Oct 24, 2009 2:14 pm

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I know it's seen in aging and certain diets.. but what is it?

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3Biochem. Question Empty Re: Biochem. Question Sat Oct 24, 2009 8:25 pm

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Modifications known as advanced glycolsylation end products (AGE) have been implicated in aging, arteriosclerosis, and diabetes, as well as other pathological conditions. AGE is the name given to a series of reactions between an amino group not participating in a peptide bond in a protein and the aldehyde form of a carbohydrate.

(Tymoczko, John L.. Biochemistry: A Short Course. W.H. Freeman & Company 9.1.1).
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